• Lipidomics in ulcerative colitis reveal alteration in mucosal lipid composition associated with the disease state 

      Diab, Joseph; Hansen, Terkel; Goll, Rasmus; Stenlund, Hans; Ahnlund, Maria; Jensen, Einar; Moritz, Thomas; Florholmen, Jon; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-11)
      <p><i>Background - </i>The onset of ulcerative colitis (UC) is associated with alterations in lipid metabolism and a disruption of the balance between pro- and anti-inflammatory molecules. Only a few studies describe the mucosal lipid biosignatures during active UC. Moreover, the dynamics of lipid metabolism in the remission state is poorly defined. Therefore, this study aims to characterize mucosal ...
    • Mucosal Metabolomic Profiling and Pathway Analysis Reveal the Metabolic Signature of Ulcerative Colitis 

      Diab, Joseph; Hansen, Terkel; Goll, Rasmus; Stenlund, Hans; Jensen, Einar; Moritz, Thomas; Florholmen, Jon; Forsdahl, Guro (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-27)
      The onset of ulcerative colitis (UC) is characterized by a dysregulated mucosal immune response triggered by several genetic and environmental factors in the context of host–microbe interaction. This complexity makes UC ideal for metabolomic studies to unravel the disease pathobiology and to improve the patient stratification strategies. This study aims to explore the mucosal metabolomic profile in ...